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KMID : 0385920090200010115
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Journal of the Korean Society of Emergency Medicine
2009 Volume.20 No. 1 p.115 ~ p.121
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Effect of Alcohol Ingestion on Clinical Features of Acute Drug Intoxicated Patients
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Lee Un-Jung
Choi Se-Min
Park Kyu-Nam
Woo Seon-Hee
Choi Seung-Phill
Kyong Yeon-Young
Youn Chun-Song
Jeong Si-Kyoung
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Abstract
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Purpose: This study was conducted to see the effect of alcohol ingestion on clinical features of acute drug intoxicated patients.
Methods: We prospectively investigated drug intoxicated patients who visited the emergency department 6 hours
after acute poisoning from January 2004 to December 2007. Patients were classified into two groups according to serum
alcohol levels: an alcohol group (serum alcohol level>10 mg/dl) and a non-alcohol group. The type of toxic material,
age, sex, duration of time to arrive to the emergency department (ED) after poisoning, mean arterial pressure, respiratory rate, base excess level, AST level, serum creatinine level, cause of poisoning, suicide attempt, past psychiatric history,
discharge against medical advice rate, and admission rate were checked. The initial and final Poisoning Severity Score
(PSS), the Glasgow coma scale, the length of stay in the intensive care unit (ICU), the usage of a mechanical ventilator,
and death rate were also checked.
Results: The study enrolled 222 intoxicated patients of which 75 fell into the non-alcohol group and 147 into the
alcohol group. Alcohol ingestion of acute poisoning in males was higher than in females. The AST level and discharge
against medical advice rates in the alcohol group were higher than the non-alcohol group. The base excess level,
length of stay in ICU, past psychiatric history rate, and admission rates in the non-alcohol group were higher than
the alcohol group. The PSS were not correlated with alcohol consumption between the two groups.
Conclusion: Alcohol ingestion is not associated with PSS. However, alcohol ingestion is commonly found in acute drug intoxicated patients. The discharge against medical advice rate in the alcohol group was higher than the non-alcohol group.
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KEYWORD
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Alcohol Drinking, Poisoning, Emergencies, Severity of Illness Index
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